Paraneoplastic hyperthyroidism secondary to metastatic choriocarcinoma. Clinical Case Report.

Authors

  • Mendoza M Pedro Department of Endocrinology, La Raza National Medical Center, Mexican Institute of Social Security IMSS, Mexico City
  • Plateado Salazar Erick O Department of Endocrinology, La Raza National Medical Center, Mexican Institute of Social Security IMSS, Mexico City
  • Paul Espinosa Carla J Department of Endocrinology, La Raza National Medical Center, Mexican Institute of Social Security IMSS, Mexico City

Keywords:

Hyperthyroidism, Choriocarcinoma, Metastasis

Abstract

Rarely, thyrotoxicosis may arise as a paraneoplastic syndrome, as in the case of choriocarcinoma. Similarities in biological structures between serum human chorionic gonadotropin (HCG) and thyroid stimulating hormone (TSH) allow HCG to exert its effects on the TSH receptor on thyroid membranes. Thyrotoxicosis was presented in a 25-year-old female patient who previously presented deterioration of alertness, intracranial hypertension, with subsequent finding of multiple metastatic lesions, with concentrations of human chorionic gonadotropin up to 500,000 mIU/mL. With adequate evolution after initiation of antithyroid and chemotherapy.

Objective

To report a case of rare pathology and review the literature to know the right approach to a case of paraneoplastic
hyperthyroidism.

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Published

2023-06-17

How to Cite

Pedro, M. M., Erick O, P. S., & Carla J, P. E. (2023). Paraneoplastic hyperthyroidism secondary to metastatic choriocarcinoma. Clinical Case Report. International Journal of Complementary and Internal Medicine, 5(1), 175–180. Retrieved from https://ijcimjournal.com/index.php/1/article/view/44

Issue

Vol. 5 No. 1 (2023): IJCIM

Section

Articles